ea0019oc14 | Neuroendocrine and Steroids | SFEBES2009
Arlt W
, Hahner S
, Libe R
, Hughes BA
, Biehl M
, Stiekema H
, Schneider P
, Smith DJ
, Shackleton CHL
, Opocher G
, Bertherat J
, Allolio B
, Mannelli M
, Mantero F
, Fassnacht M
, Bertagna X
, Stewart PM
Adrenal tumours have an incidence of 23% in the general population. Adrenocortical carcinoma (ACC), a highly malignant tumor with a poor prognosis, has an annual incidence of two per million but representation in pre-selected patient cohorts with adrenal masses undergoing surgery is up to 12%. Differentiating adrenocortical adenomas (ACA) from ACC represents a continuous challenge, with unfavourable sensitivities and specificities provided by tumour size, imaging criteri...